Copper-catalyzed asymmetric allylation of chiral N-tert-butanesulfinyl imines: dual stereocontrol with nearly perfect diastereoselectivity.

نویسندگان

  • Yi-Shuang Zhao
  • Qiang Liu
  • Ping Tian
  • Jing-Chao Tao
  • Guo-Qiang Lin
چکیده

Copper-catalyzed asymmetric allylation of chiral N-tert-butanesulfinyl imines has been described. Dual stereocontrol, through the combination of a chiral auxiliary and a chiral copper complex, has played an important role in achieving the nearly perfect diastereoselectivities (all dr > 99 : 1), especially for ketimine substrates.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 14  شماره 

صفحات  -

تاریخ انتشار 2015